Technical Articles

JAK

重组小鼠il-2蛋白：作为 T 细胞生长因子，它凭什么同时喂养效应 T 与调节性 T？

Recombinant Mouse IL-2: T Cell Growth Factor, Receptor Signaling and Immune Assays

2026-10-13

Mouse IL-2 signals through CD25/CD122/gamma-c to activate JAK/STAT5, supporting T cell growth and Treg biology. This article explains its receptor mechanism, activity assays and immune experiment applications.

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Immunity/Inflamma
IL-2
interleukin 2
mouse IL-2
CD25
CD122
gamma-c
JAK
STAT5
Treg
UA040171

重组小鼠il-6蛋白：为什么它既按下急性期反应的开关，又常在慢性炎症里被反复研究？

Recombinant Mouse IL-6: One Cytokine Across Acute-Phase Response and Chronic Inflammation

2026-10-13

Mouse IL-6 drives the acute-phase response through classic signaling and sustains chronic inflammation via trans-signaling. This article breaks down receptor assembly, the JAK/STAT3 axis and common experimental readouts.

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Immunity/Inflamma
IL-6
interleukin 6
mouse IL-6
gp130
IL-6R
JAK
STAT3
trans-signaling
acute-phase response
UA040155

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