Technical Articles

Once known merely as the LPS sensor, TLR4 now stands at the crossroads of adjuvant development, sepsis intervention and antitumor immunity. This article moves from the structural basis of ligand recognition to its translational value.

The IL-10 family of cytokines plays a critical role in maintaining tissue homeostasis during infection and inflammation by suppressing excessive immune activation, enhancing innate immunity, and promoting tissue repair.