Technical Articles
IRF3
The TLR4/MD-2 Signaling Pathway: Ligand Recognition, Dual-Branch Transduction and Research Landscape
TLR4 signaling branches at the TIR domain into MyD88-dependent and TRIF-dependent pathways, driving NF-κB/MAPK and IRF3/interferon responses respectively. This review systematically covers pathway hierarchy, readout indicators and experimental consid
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- Immunity/Inflamma
- TLR4
- MyD88
- TRIF
- NF-κB
- IRF3
- Signaling pathway
- UA01001C-28
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