Technical Articles

This article systematically elaborates on the molecular characteristics and biological functions of interleukin-6 (IL-6), highlighting its core regulatory role as a pleiotropic inflammatory cytokine in innate and adaptive immune responses. It analyzes the multi-level functional effects of IL-6 on B cells, T cells, hepatocytes, and hematopoietic stem cells, compares its kinetic differences with other inflammatory markers, and explores its clinical application value in infectious diseases, autoimmune disorders, and tumors.

Interleukin-6 is a pleiotropic cytokine secreted by various cells (such as macrophages, T cells, fibroblasts, etc.)

Interleukin-6 (IL-6) is a single-chain glycoprotein composed of 212 amino acids, with a molecular weight of approximately 26 kDa, and its encoding gene is located on human chromosome 7p21.