Technical Articles

This article focuses on the molecular characteristics and biological functions of interleukin-4 (IL-4), systematically elaborating the molecular mechanisms by which it drives the generation of immunosuppressive myeloid cells through bone marrow hematopoiesis regulation in the tumor microenvironment, analyzing the pathological role of IL-4 as a major driver of tumor-infiltrating monocyte-derived macrophages, and exploring the potential clinical value of targeting the IL-4 signaling pathway in tumor immunotherapy.