Technical Articles

IL-31RA
重组人il-31, canine蛋白是什么？il-31, canine靶点蛋白在犬皮肤瘙痒模型里怎么用｜IL-31 Protein, Canine (UA040130)
What Is Canine IL-31: How the Itch Cytokine Drives Dermatitis Models
发布时间 2026-10-26
Canine IL-31 signals through IL-31RA/OSMR and drives chronic itch in atopic dermatitis. This article covers the mechanism and how recombinant canine IL-31 supports model work.
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  • Immunity/Inflamma
  • Canine IL-31
  • IL-31RA
  • OSMR
  • pruritus
  • atopic dermatitis
  • itch model
  • UA040130
以IL-31RA为靶点：瘙痒治疗的新机制与前景
Targeting IL-31RA: A New Mechanism and Prospect for Itching Treatment
发布时间 2025-09-01
The interleukin-31 receptor alpha subunit (IL-31RA) has become an important target in the treatment of chronic inflammatory skin diseases. As a receptor primarily expressed on the surface of peripheral sensory neurons and some immune cells, IL-31RA activates downstream signaling pathways upon binding to the ligand IL-31, directly participating in the generation and transmission of itch signals.
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  • Immunity/Inflamma
  • IL-31RA
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