Technical Articles

IL-2R alpha
三把钥匙一把锁：IL-2 与受体三元复合物的组装故事
Three Keys, One Lock: How IL-2 Assembles Its Ternary Receptor Complex
发布时间 2026-09-22
IL-2 activates T cells like opening a triple lock: first captured by IL-2R alpha (CD25), then completed into the high-affinity complex by the beta chain (CD122) and gamma-c (CD132). The three-tier affinity transition underlies the bipolar nature of I
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  • Immunity/Inflamma
  • IL-2
  • IL-2R alpha
  • CD25
  • CD122
  • CD132
  • ternary complex
  • affinity
Total 1
  • 1
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