Technical Articles

This article focuses on the molecular characteristics and biological functions of interleukin‑27 (IL‑27). It systematically describes the pleiotropic effects of this IL‑6 family member in immune regulation through the IL‑27R/JAK‑STAT signaling pathway, analyzes the dual regulatory mechanisms of IL‑27 in anti‑tumor responses, obesity-associated inflammation and autoimmune diseases, and discusses its inhibitory effects during viral infection.