Technical Articles

This article focuses on the molecular characteristics and biological functions of interleukin‑10 (IL‑10). It systematically elaborates the molecular mechanism by which this potent anti-inflammatory cytokine suppresses the expression of inflammatory factors via the IL‑10R/JAK‑STAT signaling pathway, analyzes the dual regulatory roles of IL‑10 in acute infection, persistent infection and viral immune escape, and explores the association between IL‑10 gene polymorphisms and disease susceptibility as well as therapeutic strategies for IL‑10-related diseases.