Technical Articles

HGF is the sole ligand of c-MET, driving epithelial morphogenesis, repair and regeneration. This article explains the pro-HGF to active HGF chain and c-MET signaling.

The hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal epithelial transition factor (Met), is a receptor tyrosine kinase (RTK) that plays an important role in normal physiological processes and the occurrence and development of various diseases.