Technical Articles

This article focuses on the molecular characteristics and biological functions of Glypican-1 (GPC1), systematically elaborating its specific enrichment features as a cell surface proteoglycan in cancer cell-derived exosomes, analyzing the diagnostic sensitivity and specificity of GPC1-positive circulating exosomes as non-invasive biomarkers for pancreatic cancer, and exploring the application value of GPC1 in tumor burden monitoring, surgical prognosis assessment, and early screening.