Technical Articles

This article systematically elucidates the central driving role of EGFR as a receptor tyrosine kinase in tumorigenesis and development, as well as the impact of its mutation types on drug development, focusing on the technical principles and application systems of the EGFR kinase activity detection kit. It analyzes the advantages of homogeneous detection methods based on TR-FRET and ADP quantification compared to traditional techniques, and explores the application strategies of this kit in EGFR inhibitor screening, mutant selectivity evaluation, and resistance mechanism research.