Technical Articles

E3 ligase
生物素标记人biotinylated crbn/ddb1蛋白是什么？biotinylated crbn/ddb1靶点蛋白怎么用在PROTAC降解研究｜Biotinylated CRBN/DDB1 Protein (UA080262)
What Is Biotinylated CRBN/DDB1: How the Labeled Complex Serves PROTAC Degradation Research
发布时间 2026-10-26
Biotinylated CRBN/DDB1 is the substrate-recognition module of CRL4 E3 ligase, immobilized for binding assays. This article explains its role in PROTAC and molecular-glue studies.
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  • Drug Research
  • Biotinylated CRBN/DDB1
  • CRL4
  • E3 ligase
  • PROTAC
  • molecular glue
  • TR-FRET
  • ternary complex
  • UA080262
靶向蛋白降解技术中的CRBN E3连接酶及其应用优势
The CRBN E3 ligase in targeted protein degradation technology and its application advantages
发布时间 2026-01-05
Targeted Protein Degradation (TPD) technology is a hot field in recent drug development.
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  • Drug Research
  • VAV1/CRBN PROTAC Kit
  • Targeted protein degradation
  • E3 ligase
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