Technical Articles
Decoy receptor
The Immune System's Decoy Keys: How DcR3 Intercepts Three Death Signals
2026-09-20As a soluble decoy receptor, DcR3 intercepts FasL, LIGHT and TL1A one after another. Following the process of ligand departure, key swap and signal shutdown, this article dissects the decoy mechanism and the logic of its experimental validation.
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- Immunity/Inflamma
- DcR3
- Decoy receptor
- FasL
- LIGHT
- TL1A
- Tumor immune evasion
- UA019076
IFNGR1 Fc Chimera Protein: The "Precision Interceptor" of Gamma Interferon Signaling and a Key Probe in Immune Disease Research
2025-12-08IFNGR1 Fc Chimera is an innovative recombinant fusion protein created by fusing the extracellular ligand-binding domain of human gamma interferon receptor 1 with the antibody Fc fragment. It serves as a "high-affinity decoy receptor" for IFN-γ signaling, enabling precise modulation or blockade of this pivotal immune pathway in scientific research and translational medicine.
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- Immunity/Inflamma
- IFNGR1 Fc Chimera
- Gamma Interferon Receptor (IFN-γR)
- IFN-γ Signaling Pathway
- Decoy Receptor
- Immune Regulation
- 1
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