Technical Articles

CD19 is the B-cell co-receptor that amplifies BCR signaling through PI3K. This article maps its Ig-like domains, membrane partners and the signaling logic behind B-cell biology.

The immune system in the human body has functions such as immune surveillance, immune defense, and immune homeostasis. Its ability to resist the invasion of foreign pathogens and eliminate malignant mutations and senescent cells is primarily achieved through the innate immune system, composed of macrophages and basophils, as well as the adaptive immune system, consisting of T lymphocytes and B lymphocytes.

In the field of immunotherapy, CD19 has become a highly anticipated "star target". Scientists, clinicians and patients have high hopes for it. So, why is CD19 so important? What role does it play in immunotherapy? Today, let us step into the world of CD19 and unveil its mystery.