Technical Articles

CD124

IL-4R alpha Binding Assays: Where Flat Curves Usually Come From

2026-10-21

A troubleshooting guide for IL-4R alpha binding experiments: receptor orientation, ligand pairing, coating format and control design when binding curves stay flat or fail to reach plateau.

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Immunity/Inflamma
binding assay
IL-4R alpha
CD124
ELISA
receptor-ligand pairing
control design
signal troubleshooting
UA010382

重组人il-4r alpha/cd124蛋白：一个亚基，怎么同时接住 IL-4 和 IL-13？

IL-4R alpha/CD124: How One Shared Subunit Serves Both IL-4 and IL-13

2026-10-21

IL-4R alpha (CD124) is the common subunit of the type I and type II IL-4 receptor complexes. This article explains how one receptor chain accommodates both IL-4 and IL-13 signaling.

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Immunity/Inflamma
IL-4R alpha
CD124
IL-4
IL-13
type II receptor
STAT6
Th2
receptor complex
UA010382

Exploring IL-4R α/CD124: Key Regulators in the Immune System and Their Clinical Significance

2025-08-29

IL-4Rα， Also known as CD124, it is the core subunit of interleukin-4 receptor (IL-4R) and belongs to the type I cytokine receptor family. It can bind to two ligands: IL-4 and IL-13.

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Immunity/Inflamma
IL-4Rα
CD124
免疫

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