Technical Articles

IL-15/IL-15Rα信号轴:免疫调控枢纽与抗肿瘤策略核心
The IL-15/IL-15Rα Signaling Axis: A Pivotal Hub in Immune Regulation and Core Strategy for Anti-Tumor Therapy
发布时间 2026-08-03
This article systematically elaborates on the molecular characteristics of IL-15, its cellular sources, and its unique receptor trans-presentation mechanism. It analyzes the extensive regulatory functions of this signaling axis on key immune cell populations such as NK cells and memory CD8+ T cells through multiple pathways including JAK/STAT, PI3K/AKT, and MAPK.
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  • Immunity/Inflamma
  • Biotinylated Human IL-15 Receptor Alpha Protein
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