Technical Articles

Biotinylated CD3E/CD3D Heterodimer Protein

CD3E/CD3D异二聚体：TCR-CD3复合物的核心信号模块与双抗研发关键靶点

CD3E/CD3D heterodimer: The core signaling module of the TCR-CD3 complex and a key target for bispecific antibody development

2026-07-24

This article systematically elaborates on the structural basis and signal transduction functions of CD3E and CD3D within the TCR-CD3 complex, analyzes the physiological necessity of their formation as heterodimers, and discusses their significance as targets in antibody drug development. It also introduces the application value of biotinylated CD3E/CD3D heterodimeric recombinant proteins in the screening and evaluation of bispecific antibodies.

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Immunity/Inflamma
Biotinylated CD3E/CD3D Heterodimer Protein

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