Technical Articles
Beta-Klotho
A Door That Needs Two Keys: How FGF19, FGFR4 and KLB Open the Gate
2026-09-20The FGFR4 door opens only when both keys—FGF19 and KLB—are inserted at the same time. This article walks through the four-step assembly of the FGF19-FGFR4-KLB ternary complex and the full process of signal entry.
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- Signaling Pathway
- FGFR4
- FGF19
- Beta-Klotho
- KLB
- Ternary complex
- Hepatocellular carcinoma
- UA011375
- 1
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