Technical Articles

Directly labeled BCMA protein with Alexa Fluor 647 enables one-step flow cytometric detection of CAR expression. This article explains why the dye reads directly and how conjugation quality shapes the signal.

B cell maturation antigen (BCMA), also known as TNFRSF17, is a member of the tumor necrosis factor receptor superfamily. It is mainly expressed on the surface of mature B lymphocytes and long-lived plasma cells, playing a key role in regulating B cell differentiation, survival, and antibody production.

B-cell maturation antigen (BCMA), also known as TNFRSF17 or CD269, is an important member of the tumor necrosis factor receptor superfamily (TNFRSF). In recent years, BCMA has garnered significant attention as a therapeutic target for multiple myeloma and other B-cell malignancies.

At the forefront of medical research, the target BCMA (B cell maturation antigen) is gradually becoming a new focus of immunotherapy. Initially, BCMA was mainly focused on its potential in the treatment of multiple myeloma (MM), but recent research breakthroughs have given us new hope for its use in the treatment of autoimmune diseases.