Technical Articles

Directly labeled BCMA protein with Alexa Fluor 647 enables one-step flow cytometric detection of CAR expression. This article explains why the dye reads directly and how conjugation quality shapes the signal.

CD38, also known as cyclic ADP-ribose hydrolase, is a glycoprotein widely expressed on the surface of various cells. It plays a crucial role in immune system regulation, cell activation, proliferation, and differentiation. For instance, in lymphocytes, the expression level of CD38 is closely related to the activation state of the cells, and it is involved in the proliferation, differentiation, and cytokine secretion regulation of T cells and B cells. In myeloma cells, CD38 is highly expressed, making it a key target for the diagnosis and treatment of multiple myeloma.