Technical Articles

ActRIIA 激酶抑制剂筛选:从体系验证到 IC50 的实操指南
ActRIIA Kinase Inhibitor Screening: A Practical Guide from Assay Validation to IC50
发布时间 2026-09-21
A step-by-step SOP for ActRIIA kinase inhibitor screening: enzyme concentration titration, Z' factor acceptance thresholds, positive control LDN-193189 dilution design, luminescence readout linearity and the four most common failure nodes with troubl
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  • Signaling Pathway
  • ActRIIA kinase activity assay
  • inhibitor screening
  • Z' factor
  • IC50
  • luminescence
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